Across TCGA patient cohorts, SATB1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,753 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SATB1-associated genes across cancer lineages are HSPB1, GAA, and ACTG1. Each is linked with SATB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SATB1-to-partner and partner-to-SATB1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB1→partner) and Y-score (partner→SATB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HSPB1 →	-1.523	-0.653	<.001	<.001	3	2
LUAD	GAA →	-1.016	-1.236	<.001	.006	3	2
LUAD	ACTG1 →	-0.516	-1.167	.002	.001	3	2
BRCA	C8orf44 →	-0.699	-0.853	.003	.003	3	2
GBM	TTC3 →	+0.423	+0.455	.005	.004	3	2
LSCC	SATB1-AS1 →	+0.626	+0.457	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,753 associations by consensus.

Exploration

SATB1 survival (RNA) · tumor vs normal (RNA) · all SATB1 data types