Across TCGA patient cohorts, SATB1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SATB1-associated genes across cancer lineages are Rad50, ATM, and Caspase-7-cleavedD198. Each is linked with SATB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SATB1-to-partner and partner-to-SATB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB1→partner) and Y-score (partner→SATB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.165	-1.415	.028	.010	3	3
UCEC	ATM →	-0.445	-1.893	.001	<.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.387	+1.341	.035	.043	3	3
COAD	PDCD4 →	-0.433	-2.991	.047	.036	3	3
SKCM	STAT3_pY705 →	-0.304	-2.425	.006	.017	3	2
UCEC	Ku80 →	+0.195	+1.290	.007	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

SATB1 survival (RNA) · tumor vs normal (RNA) · all SATB1 data types