Across TCGA cell cohorts, SATB1 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SATB1-associated genes across cancer lineages are EIF3L, A4GNT, and CHIT1. Each is linked with SATB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SATB1-to-partner and partner-to-SATB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB1→partner) and Y-score (partner→SATB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	EIF3L →	+0.505	+3.087	.005	.006	3	1
LARGE_INTESTINE	A4GNT →	+0.059	+2.614	<.001	.001	3	1
LARGE_INTESTINE	CHIT1 →	+0.043	+2.807	.005	.003	3	1
LARGE_INTESTINE	SLC25A48 →	+0.929	+3.364	<.001	.002	3	1
LARGE_INTESTINE	HIGD2A →	+0.557	+3.364	.004	.002	3	1
LARGE_INTESTINE	DRAM2 →	+0.514	+3.364	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration

SATB1 survival (RNA) · tumor vs normal (RNA) · all SATB1 data types