SASH3

Across TCGA patient cohorts, SASH3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,518 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SASH3-associated genes across cancer lineages are CYTH4, APOBEC3H, and GRAP2. Each is linked with SASH3 in more than 9 cancer types. Because this analysis shows association rather than direction, both SASH3-to-partner and partner-to-SASH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SASH3 versus CYTH4 in GBM, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SASH3→partner) and Y-score (partner→SASH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.230	+0.630	<.001	<.001	3	10
BRCA	APOBEC3H →	+0.805	+0.454	<.001	<.001	3	10
OV	GRAP2 →	+0.879	+0.539	<.001	<.001	3	10
OV	NCF4 →	+1.429	+0.731	<.001	<.001	3	10
OV	CSF2RB →	+1.519	+0.655	<.001	<.001	3	10
OV	IL2RB →	+1.500	+0.601	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,518 associations by consensus.

SASH3 vs CYTH4 — GBM

Explore this scatter interactively →