SART3

Across TCGA patient cohorts, SART3 mutation is significantly associated with the RNA expression of many other genes, with 5,050 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SART3-associated genes across cancer lineages are FECH, IMP3P2, and MIR4510. Each is linked with SART3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SART3-to-partner and partner-to-SART3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FECH grouped by SART3-low versus SART3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SART3→partner) and Y-score (partner→SART3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FECH →	+0.544	+1.600	<.001	.005	3	4
HNSC	IMP3P2 →	+0.161	+3.636	<.001	.004	3	3
HNSC	MIR4510 →	+0.370	+4.468	<.001	.006	3	3
COAD	MCAT →	+0.441	+3.251	.003	.008	3	3
UCEC	MTHFD1 →	+0.437	+2.158	<.001	<.001	3	3
UCEC	ADNP2 →	+0.671	+1.606	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,050 associations by consensus.

FECH by SART3 expression — UCEC

Explore this box plot interactively →