SART3

Across TCGA cell cohorts, SART3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,097 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SART3-associated GO terms across cancer lineages are Regulation of DNA repair, Regulation of chromatin organization, and Regulation of DNA-templated transcription elongation. Each is linked with SART3 in more than 17 cancer types. Because this analysis shows association rather than direction, both SART3-to-partner and partner-to-SART3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by SART3-low versus SART3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SART3→partner) and Y-score (partner→SART3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of DNA repair →	+0.059	+0.405	<.001	<.001	3	18
SOFT_TISSUE	Regulation of chromatin organization →	+0.094	+1.115	<.001	<.001	3	18
SOFT_TISSUE	Regulation of DNA-templated transcription elongation →	+0.075	+1.068	<.001	<.001	3	18
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.081	+1.157	<.001	<.001	3	18
SOFT_TISSUE	Nucleic acid transport →	+0.104	+1.120	<.001	<.001	3	18
SOFT_TISSUE	RNA transport →	+0.104	+1.120	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,097 associations by consensus.

Regulation of DNA repair by SART3 expression — LUNG_SCLC

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