SART3

Across TCGA cell cohorts, SART3 mutation is significantly associated with the RNA expression of many other genes, with 189 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SART3-associated genes across cancer lineages are LIM2, SNU13, and SH3GL2. Each is linked with SART3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SART3-to-partner and partner-to-SART3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIM2 grouped by SART3-low versus SART3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SART3→partner) and Y-score (partner→SART3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LIM2 →	+1.471	+4.930	<.001	.008	3	1
LARGE_INTESTINE	SNU13 →	+0.409	+3.628	.008	<.001	3	1
LARGE_INTESTINE	SH3GL2 →	+0.889	+2.502	.007	.005	3	1
LARGE_INTESTINE	EXOSC3 →	+0.418	+2.502	.005	.005	3	1
LARGE_INTESTINE	PIGL →	+0.621	+2.502	.009	.005	3	1
LARGE_INTESTINE	C1QBP →	+0.835	+3.301	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 189 associations by consensus.

LIM2 by SART3 expression — SOFT_TISSUE

Explore this box plot interactively →