SART1

Across TCGA patient cohorts, SART1 mutation is significantly associated with the RNA expression of many other genes, with 1,912 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SART1-associated genes across cancer lineages are CDRT15P11, EME1, and CCNB2. Each is linked with SART1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SART1-to-partner and partner-to-SART1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDRT15P11 grouped by SART1-low versus SART1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SART1→partner) and Y-score (partner→SART1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDRT15P11 →	+0.030	+5.108	<.001	.002	3	2
UCEC	EME1 →	+0.505	+2.265	.003	.005	3	2
UCEC	CCNB2 →	+0.539	+2.732	.009	.003	3	2
UCEC	NDUFAF2 →	+0.505	+2.233	.001	.005	3	2
UCEC	SAAL1 →	+0.384	+1.923	.008	.009	3	2
SKCM	PPIP5K1 →	+0.514	+3.465	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,912 associations by consensus.

CDRT15P11 by SART1 expression — LUAD

Explore this box plot interactively →