SARS2

Across TCGA cell cohorts, SARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,783 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SARS2-associated GO terms across cancer lineages are tRNA aminoacylation for protein translation, Epigenetic regulation of gene expression, and Amino acid activation. Each is linked with SARS2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SARS2-to-partner and partner-to-SARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA aminoacylation for protein translation grouped by SARS2-low versus SARS2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SARS2→partner) and Y-score (partner→SARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	tRNA aminoacylation for protein translation →	+0.081	+0.869	<.001	<.001	3	16
BONE	Epigenetic regulation of gene expression →	+0.073	+1.019	<.001	.001	3	14
LIVER	Amino acid activation →	+0.094	+1.071	.001	.006	3	14
LIVER	tRNA aminoacylation →	+0.094	+1.071	.001	.006	3	14
BONE	DNA replication proofreading →	+0.276	+1.378	<.001	<.001	3	14
SOFT_TISSUE	Leading strand elongation →	+0.156	+1.003	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,783 associations by consensus.

tRNA aminoacylation for protein translation by SARS2 expression — CNS

Explore this box plot interactively →