SARS2

Across TCGA cell cohorts, SARS2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,882 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SARS2-associated genes across cancer lineages are ZNF791, STX10, and CD109. Each is linked with SARS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SARS2-to-partner and partner-to-SARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SARS2 versus ZNF791 in OESOPHAGUS, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SARS2→partner) and Y-score (partner→SARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ZNF791 →	+0.581	+0.996	.009	.008	3	4
LUNG_NSCLC_LUAD	STX10 →	+0.541	+1.078	.001	.001	3	4
BLOOD_Leukemia	CD109 →	+1.762	+1.155	<.001	<.001	3	4
BREAST	NAF1 →	-0.728	-0.862	<.001	.001	3	4
KIDNEY	TRIM68 →	-0.804	-0.772	<.001	<.001	3	4
SOFT_TISSUE	TMEM14A →	+0.833	+1.181	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,882 associations by consensus.

SARS2 vs ZNF791 — OESOPHAGUS

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