SARM1

Across TCGA patient cohorts, SARM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,283 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SARM1-associated proteins across cancer lineages are RPA3, NFYA_S326, and PGAM1_S31. Each is linked with SARM1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SARM1-to-partner and partner-to-SARM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SARM1 versus RPA3 in PDAC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SARM1→partner) and Y-score (partner→SARM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RPA3 →	+0.412	+0.316	<.001	<.001	3	6
PDAC	NFYA_S326 →	+0.718	+0.283	.001	.001	3	5
HNSC	PGAM1_S31 →	-0.602	-0.590	<.001	<.001	3	5
HNSC	VEZF1 →	+0.481	+0.731	<.001	<.001	3	5
HNSC	TCEAL1 →	+0.528	+0.568	<.001	<.001	3	5
LUAD	TNKS1BP1_S1138 →	-0.550	-0.379	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,283 associations by consensus.

SARM1 vs RPA3 — PDAC

Explore this scatter interactively →