SARAF

Across TCGA patient cohorts, SARAF mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SARAF-associated genes across cancer lineages are CD8+ T-cells. Each is linked with SARAF in more than 1 cancer types. Because this analysis shows association rather than direction, both SARAF-to-partner and partner-to-SARAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by SARAF-low versus SARAF-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SARAF→partner) and Y-score (partner→SARAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	CD8+ T-cells →	+0.039	+5.453	<.001	.044	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD8+ T-cells by SARAF expression — PRAD

Explore this box plot interactively →