SAR1B

Across TCGA patient cohorts, SAR1B protein abundance is significantly associated with the RNA expression of many other genes, with 16,458 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAR1B-associated genes across cancer lineages are ZNF286A, SNHG20, and CASC15. Each is linked with SAR1B in more than 5 cancer types. Because this analysis shows association rather than direction, both SAR1B-to-partner and partner-to-SAR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAR1B versus ZNF286A in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAR1B→partner) and Y-score (partner→SAR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF286A →	-0.597	-0.372	<.001	.001	3	6
LSCC	SNHG20 →	-0.422	-0.253	<.001	.001	3	6
LUAD	CASC15 →	-0.952	-0.277	<.001	<.001	3	6
LSCC	UBXN2A →	-0.424	-0.239	<.001	<.001	3	6
BRCA	ASXL1 →	-0.603	-0.462	<.001	<.001	3	5
OV	SNHG17 →	-0.602	-0.415	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,458 associations by consensus.

SAR1B vs ZNF286A — HNSC

Explore this scatter interactively →