SAR1B

Across TCGA cell cohorts, SAR1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,987 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SAR1B-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Endoplasmic reticulum to Golgi vesicle-mediated transport, and CAAX-box protein maturation. Each is linked with SAR1B in more than 13 cancer types. Because this analysis shows association rather than direction, both SAR1B-to-partner and partner-to-SAR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by SAR1B-low versus SAR1B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAR1B→partner) and Y-score (partner→SAR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.142	+1.072	<.001	<.001	3	13
LIVER	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.080	+0.916	.004	<.001	2	14
BONE	CAAX-box protein maturation →	+0.135	+0.794	<.001	.003	3	12
BONE	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.117	+0.963	.002	<.001	3	12
LUNG_SCLC	Lipid export from cell →	+0.253	+0.709	<.001	.003	3	12
STOMACH	Regulation of COPII vesicle coating →	+0.226	+1.055	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,987 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by SAR1B expression — BONE

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