SAPCD2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SAPCD2 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of SAPCD2’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SAPCD2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SAPCD2 is over-expressed in tumor.

BLCA, COAD, and LUAD are the cancer types where SAPCD2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SAPCD2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BLCAMaleIII,IV+3.941<.00112view →
COADMaleIII,IV+2.353<.00112view →
LUADMaleIII,IV+3.448<.00111view →
THCAAllIII,IV+0.719<.00110view →
LUSCAllIII,IV+3.974<.0019view →
STADAllII,III,IV+2.627<.0019view →
UCECAllIII,IV+4.072<.0018view →
HNSCMaleIV+1.522<.0018view →
LIHCFemaleAll+1.059<.0018view →
BRCAAllIII,IV+1.680<.0016view →
READAllAll+1.843<.0015view →
KICHAllAll+1.224<.0015view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

Exploration