SAP30L

Across TCGA pan-cancer cohorts, SAP30L Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SAP30L data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SAP30L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SAP30L expression acts as an unfavorable survival marker.

HNSC and CHOL are the cancer types where SAP30L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.098	0.746	<.001	24	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SAP30L–HNSC (OS)

Open the HNSC breakdown →