SAP30L-AS1

Across TCGA pan-cancer cohorts, SAP30L-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SAP30L-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SAP30L-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SAP30L-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, LIHC, and KIRC are the cancer types where SAP30L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.446	0.325	<.001	128	view →
LIHC	DFS	Median	All	0.475	0.609	<.001	64	view →
KIRC	DFS	Quartile	III,IV	0.230	0.557	.009	60	view →
LGG	DFS	Tertile	All	0.324	0.494	<.001	38	view →
ACC	OS	Quartile	All	0.305	0.909	.001	34	view →
KICH	DFS	Tertile	III,IV	0.279	1.000	.022	33	view →
READ	OS	Quartile	II,III,IV	0.858	0.328	.004	28	view →
BRCA	OS	Quartile	IV	0.723	0.228	.004	23	view →
KIRP	DFS	Quartile	All	0.596	0.827	<.001	22	view →
MESO	DFS	Median	III,IV	0.282	0.452	.012	15	view →
SKCM	OS	Quartile	III,IV	0.595	0.306	.009	15	view →
THCA	DFS	Quartile	IV	0.430	0.839	.011	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SAP30L-AS1–HNSC (OS)

Open the HNSC breakdown →