SAP30BP

Across TCGA pan-cancer cohorts, SAP30BP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SAP30BP data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SAP30BP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SAP30BP expression acts as an unfavorable survival marker.

HNSC, BLCA, and LUSC are the cancer types where SAP30BP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.170	0.769	<.001	48	view →
BLCA	DFS	Median	IV	0.090	0.469	.009	12	view →
LUSC	DFS	Median	II,III,IV	0.185	0.717	.012	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SAP30BP–HNSC (OS)

Open the HNSC breakdown →