SAP30

Across TCGA pan-cancer cohorts, SAP30 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SAP30 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SAP30 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SAP30 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LUAD, LSCC, and PDAC are the cancer types where SAP30 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.443	0.780	.002	24	view →
LSCC	OS	Tertile	All	0.899	0.660	.009	16	view →
PDAC	DFS	Tertile	III,IV	0.493	0.902	.019	9	view →
HNSC	OS	Median	All	1.000	0.959	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SAP30–LUAD (DFS)

Open the LUAD breakdown →