Across TCGA patient cohorts, SAP25 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SAP25-associated GO terms across cancer lineages are Spermidine metabolic process, Regulation of DNA strand elongation, and Phosphatidylcholine metabolic process. Each is linked with SAP25 in more than 25 cancer types. Because this analysis shows association rather than direction, both SAP25-to-partner and partner-to-SAP25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP25→partner) and Y-score (partner→SAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Spermidine metabolic process →	+0.171	+1.410	<.001	<.001	3	26
KIRC	Regulation of DNA strand elongation →	+0.062	+0.436	<.001	<.001	3	26
KIRC	Phosphatidylcholine metabolic process →	+0.049	+0.433	<.001	<.001	3	25
KIRC	High-density lipoprotein particle assembly →	+0.087	+0.367	<.001	<.001	3	25
SCLC	Positive regulation of DNA repair →	+0.072	+1.436	<.001	<.001	2	26
KIRC	Negative regulation of protein K63-linked ubiquitination →	+0.087	+0.472	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Exploration

SAP25 survival (RNA) · tumor vs normal (RNA) · all SAP25 data types