Across TCGA patient cohorts, SAP25 protein abundance is significantly associated with the RNA expression of many other genes, with 82 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAP25-associated genes across cancer lineages are SLC35E4, FBXL5, and NMI. Each is linked with SAP25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP25-to-partner and partner-to-SAP25 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP25→partner) and Y-score (partner→SAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC35E4 →	+1.280	+2.763	.008	.002	3	1
LSCC	FBXL5 →	-0.903	-2.700	<.001	.002	3	1
LSCC	NMI →	-0.783	-2.743	.005	.002	3	1
LSCC	CYP2C19 →	+0.453	+2.743	.006	.002	3	1
LSCC	ZIK1 →	-2.356	-2.723	.001	.002	3	1
LSCC	SAGE1 →	+5.370	+2.656	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

Exploration

SAP25 survival (RNA) · tumor vs normal (RNA) · all SAP25 data types