Across TCGA patient cohorts, SAP25 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAP25-associated genes across cancer lineages are CTHRC1P1, MYOM3-AS1, and MTND2P17. Each is linked with SAP25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP25-to-partner and partner-to-SAP25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP25→partner) and Y-score (partner→SAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CTHRC1P1 →	+0.226	+4.694	<.001	.007	3	1
UCEC	MYOM3-AS1 →	+0.159	+4.551	.004	.009	3	1
UCEC	MTND2P17 →	+0.101	+5.027	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

SAP25 survival (RNA) · tumor vs normal (RNA) · all SAP25 data types