Across TCGA cell cohorts, SAP25 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,772 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAP25-associated GO terms across cancer lineages are Positive regulation of toll-like receptor signaling pathway, Viral transcription, and Late viral transcription. Each is linked with SAP25 in more than 9 cancer types. Because this analysis shows association rather than direction, both SAP25-to-partner and partner-to-SAP25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP25→partner) and Y-score (partner→SAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of toll-like receptor signaling pathway →	+0.157	+1.076	<.001	<.001	3	10
BONE	Viral transcription →	+0.136	+1.007	<.001	<.001	3	9
BONE	Late viral transcription →	+0.151	+0.887	.001	.001	3	9
BONE	Pre-mRNA catabolic process →	+0.254	+1.066	<.001	<.001	3	8
OVARY	Activation of transmembrane receptor protein tyrosine kinase activity →	+0.392	+1.592	.007	.001	3	8
LUNG_SCLC	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.103	+1.051	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,772 associations by consensus.

Exploration

SAP25 survival (RNA) · tumor vs normal (RNA) · all SAP25 data types