Across TCGA cell cohorts, SAP25 protein abundance is significantly associated with the RNA expression of many other genes, with 2,252 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SAP25-associated genes across cancer lineages are CLPTM1, NECTIN2, and BCL2L12. Each is linked with SAP25 in more than 9 cancer types. Because this analysis shows association rather than direction, both SAP25-to-partner and partner-to-SAP25 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP25→partner) and Y-score (partner→SAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CLPTM1 →	+1.319	+2.069	.004	.007	2	10
STOMACH	NECTIN2 →	+1.709	+1.555	.001	.003	2	8
LUNG_SCLC	BCL2L12 →	+2.012	+1.029	.003	.006	3	6
LIVER	SOX9 →	+3.202	+0.821	.001	.007	3	5
OVARY	NFKBIB →	+0.829	+1.190	.008	.006	2	6
LUNG_NSCLC_LUAD	OPA3 →	+0.509	+0.841	.002	.009	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,252 associations by consensus.

Exploration

SAP25 survival (RNA) · tumor vs normal (RNA) · all SAP25 data types