Across TCGA cell cohorts, SAP25 mutation is significantly associated with the mutation status of many other genes, with 180 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAP25-associated genes across cancer lineages are CNEP1R1, ETFRF1, and SLCO1B7. Each is linked with SAP25 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAP25-to-partner and partner-to-SAP25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAP25→partner) and Y-score (partner→SAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CNEP1R1 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	ETFRF1 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	SLCO1B7 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	C22orf42 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	KLK9 →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	DNASE1 →	+4.523	+5.087	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

Exploration

SAP25 survival (RNA) · tumor vs normal (RNA) · all SAP25 data types