Across TCGA pan-cancer cohorts, SAP18P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SAP18P2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SAP18P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SAP18P2 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

COAD, PAAD, and HNSC are the cancer types where SAP18P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SAP18P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.352	<.001	5	view →
PAAD	Female	All	−0.390	.049	2	view →
HNSC	Male	All	+0.052	.030	2	view →
LUSC	All	All	+0.034	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SAP18P2 RNA expression & survival · all SAP18P2 data types