SAMSN1

Across TCGA cell cohorts, SAMSN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,082 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SAMSN1-associated GO terms across cancer lineages are Positive regulation of protein deubiquitination, Ribosome-associated ubiquitin-dependent protein catabolic process, and Regulation of CD4-positive, alpha-beta T cell activation. Each is linked with SAMSN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SAMSN1-to-partner and partner-to-SAMSN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein deubiquitination grouped by SAMSN1-low versus SAMSN1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMSN1→partner) and Y-score (partner→SAMSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of protein deubiquitination →	+0.128	+2.008	<.001	<.001	3	5
BLOOD_Leukemia	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.037	+1.753	.006	.001	3	5
BLOOD_Leukemia	Regulation of CD4-positive, alpha-beta T cell activation →	+0.069	+2.763	<.001	<.001	3	5
BLOOD_Lymphoma	T cell lineage commitment →	+0.122	+1.775	.001	.001	3	5
BLOOD_Lymphoma	Complement activation, alternative pathway →	+1.039	+1.911	<.001	<.001	3	5
PANCREAS	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.033	-0.339	.006	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,082 associations by consensus.

Positive regulation of protein deubiquitination by SAMSN1 expression — BLOOD_Lymphoma

Explore this box plot interactively →