Across TCGA patient cohorts, SAMD9 mutation is significantly associated with the RNA expression of many other genes, with 4,916 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAMD9-associated genes across cancer lineages are MTND4P33, SERP2, and DSCR4-IT1. Each is linked with SAMD9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAMD9-to-partner and partner-to-SAMD9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD9→partner) and Y-score (partner→SAMD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MTND4P33 →	+0.061	+4.883	<.001	.004	3	3
COAD	SERP2 →	-0.883	-3.700	.001	.001	3	3
SKCM	DSCR4-IT1 →	+0.305	+1.152	<.001	.002	3	3
LUSC	CTAG1B →	+0.060	+2.524	<.001	.008	3	3
LUAD	CORO2B →	-0.550	-2.871	.001	.001	3	3
LUAD	PRG4 →	-0.934	-3.789	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,916 associations by consensus.

Exploration

SAMD9 survival (RNA) · tumor vs normal (RNA) · all SAMD9 data types