Across TCGA cell cohorts, SAMD9 mutation is significantly associated with the RNA expression of many other genes, with 154 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAMD9-associated genes across cancer lineages are PRAMEF1, DGAT2L6, and COPS3. Each is linked with SAMD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD9-to-partner and partner-to-SAMD9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD9→partner) and Y-score (partner→SAMD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	PRAMEF1 →	+0.033	+4.121	<.001	.006	3	2
BLOOD_Lymphoma	DGAT2L6 →	+0.220	+3.736	<.001	.009	3	2
LARGE_INTESTINE	COPS3 →	+0.593	+3.502	.003	.001	3	2
LARGE_INTESTINE	SARNP →	+0.419	+3.321	.003	.003	3	2
KIDNEY	LILRB2 →	+0.066	+4.121	<.001	.006	3	1
KIDNEY	VCX2 →	+0.132	+4.954	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 154 associations by consensus.

Exploration

SAMD9 survival (RNA) · tumor vs normal (RNA) · all SAMD9 data types