Across TCGA cell cohorts, SAMD9 mutation is significantly associated with the mutation status of many other genes, with 4,130 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SAMD9-associated genes across cancer lineages are PLXNA4, MYBL2, and UNC79. Each is linked with SAMD9 in more than 4 cancer types. Because this analysis shows association rather than direction, both SAMD9-to-partner and partner-to-SAMD9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD9→partner) and Y-score (partner→SAMD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PLXNA4 →	+2.053	+3.233	.004	.004	1	5
CNS	MYBL2 →	+5.000	+4.044	.008	.008	1	5
LARGE_INTESTINE	UNC79 →	+1.761	+2.226	.001	.001	1	5
SOFT_TISSUE	ASTN2 →	+4.502	+5.066	.007	.007	1	5
CNS	TMC3 →	+4.000	+4.000	.002	.002	1	4
PANCREAS	ACE →	+5.115	+5.115	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,130 associations by consensus.

Exploration

SAMD9 survival (RNA) · tumor vs normal (RNA) · all SAMD9 data types