SAMD8

Across TCGA patient cohorts, SAMD8 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,271 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SAMD8-associated proteins across cancer lineages are ANXA7, SPARC, and ECM1. Each is linked with SAMD8 in more than 5 cancer types. Because this analysis shows association rather than direction, both SAMD8-to-partner and partner-to-SAMD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAMD8 versus ANXA7 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD8→partner) and Y-score (partner→SAMD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANXA7 →	+0.297	+0.593	<.001	<.001	3	6
OV	SPARC →	+0.655	+0.879	.003	<.001	3	5
BRCA	ECM1 →	+0.557	+0.521	<.001	.003	3	5
GBM	BAG3 →	+0.386	+0.343	<.001	<.001	3	4
PDAC	TUBB6 →	+0.590	+0.287	<.001	<.001	3	4
LUAD	DDX50 →	+0.201	+0.256	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,271 associations by consensus.

SAMD8 vs ANXA7 — BRCA

Explore this scatter interactively →