SAMD8

Across TCGA patient cohorts, SAMD8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,817 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAMD8-associated genes across cancer lineages are COMTD1, CXCL8, and CHCHD1. Each is linked with SAMD8 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAMD8-to-partner and partner-to-SAMD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAMD8 versus COMTD1 in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD8→partner) and Y-score (partner→SAMD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COMTD1 →	+1.310	+0.518	<.001	<.001	3	3
HNSC	CXCL8 →	+1.851	+0.486	.002	<.001	3	3
LUAD	CHCHD1 →	+0.567	+0.531	<.001	<.001	3	3
OV	NOP56 →	+0.594	+0.551	.004	.004	3	2
OV	PSMF1 →	+0.619	+0.603	<.001	.001	3	2
OV	WDR54 →	+1.059	+0.587	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,817 associations by consensus.

SAMD8 vs COMTD1 — BRCA

Explore this scatter interactively →