Across TCGA cell cohorts, SAMD7 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SAMD7-associated genes across cancer lineages are MROH2B, CCDC172, and OR13G1. Each is linked with SAMD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD7-to-partner and partner-to-SAMD7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD7→partner) and Y-score (partner→SAMD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MROH2B →	+0.004	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCDC172 →	+0.004	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CT45A6 →	+0.034	+4.415	<.001	.007	3	1
OVARY	BMP15 →	+0.123	+5.807	<.001	.001	3	1
OVARY	PDHA2 →	+0.006	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

SAMD7 survival (RNA) · tumor vs normal (RNA) · all SAMD7 data types