Across TCGA patient cohorts, SAMD5 mutation is significantly associated with the RNA expression of many other genes, with 1,567 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAMD5-associated genes across cancer lineages are MTND2P7, SEPTIN14P19, and RNA5SP422. Each is linked with SAMD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD5-to-partner and partner-to-SAMD5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD5→partner) and Y-score (partner→SAMD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTND2P7 →	+0.053	+7.930	.009	.008	3	2
UCEC	SEPTIN14P19 →	+0.024	+3.830	<.001	.001	3	2
UCEC	RNA5SP422 →	+0.689	+2.519	<.001	<.001	3	2
UCEC	IGKV1OR2-118 →	+0.223	+2.036	<.001	.003	3	1
UCEC	CWC25 →	+0.420	+3.119	.003	<.001	3	1
UCEC	TAF9 →	+0.628	+3.807	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,567 associations by consensus.

Exploration

SAMD5 survival (RNA) · tumor vs normal (RNA) · all SAMD5 data types