SAMD3

Across TCGA cell cohorts, SAMD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,494 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SAMD3-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Carbohydrate transport, and Protein-containing complex disassembly. Each is linked with SAMD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SAMD3-to-partner and partner-to-SAMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by SAMD3-low versus SAMD3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD3→partner) and Y-score (partner→SAMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of cytoskeleton organization →	+0.034	+0.477	<.001	.006	3	7
URINARY_TRACT	Carbohydrate transport →	-0.085	-0.551	<.001	.006	3	5
STOMACH	Protein-containing complex disassembly →	+0.067	+0.488	<.001	.004	3	5
STOMACH	GABAergic neuron differentiation →	+1.197	+0.825	<.001	.008	3	5
SOFT_TISSUE	Negative regulation of nucleotide biosynthetic process →	-0.167	-0.702	<.001	.001	3	5
SKIN	Positive regulation of actin filament bundle assembly →	+0.084	+0.704	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,494 associations by consensus.

Positive regulation of cytoskeleton organization by SAMD3 expression — SKIN

Explore this box plot interactively →