SAMD14

Across TCGA patient cohorts, SAMD14 protein abundance is significantly associated with the RNA expression of many other genes, with 911 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SAMD14-associated genes across cancer lineages are TMEM125, TBC1D3P1, and C1GALT1. Each is linked with SAMD14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD14-to-partner and partner-to-SAMD14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAMD14 versus TMEM125 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD14→partner) and Y-score (partner→SAMD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMEM125 →	+1.292	+0.243	<.001	.002	3	2
GBM	TBC1D3P1 →	-0.119	-0.264	.001	.008	3	2
LUAD	C1GALT1 →	-1.078	-0.947	<.001	<.001	3	1
LUAD	RPA3 →	-0.460	-0.593	.003	.009	3	1
LUAD	TSPAN13 →	-0.979	-0.614	.001	.007	3	1
LUAD	HMGCS1 →	-0.628	-0.611	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 911 associations by consensus.

SAMD14 vs TMEM125 — GBM

Explore this scatter interactively →