SAMD14

Across TCGA cell cohorts, SAMD14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,484 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SAMD14-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Cell division. Each is linked with SAMD14 in more than 13 cancer types. Because this analysis shows association rather than direction, both SAMD14-to-partner and partner-to-SAMD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SAMD14-low versus SAMD14-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD14→partner) and Y-score (partner→SAMD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.181	+1.266	.001	.005	3	13
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.178	+1.266	.001	.005	3	13
LUNG_SCLC	Cell division →	+0.084	+2.066	<.001	<.001	3	13
LUNG_SCLC	Nucleoside triphosphate metabolic process →	+0.094	+1.775	<.001	.004	2	14
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.054	+0.610	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.098	+0.670	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,484 associations by consensus.

Negative regulation of myoblast fusion by SAMD14 expression — OESOPHAGUS

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