Across TCGA patient cohorts, SAMD13 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SAMD13-associated genes across cancer lineages are FOXO3a, p21, and STAT3_pY705. Each is linked with SAMD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD13-to-partner and partner-to-SAMD13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD13→partner) and Y-score (partner→SAMD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	-0.151	-2.986	.010	.037	3	1
UCEC	p21 →	+0.277	+3.000	.012	.037	3	1
UCEC	STAT3_pY705 →	-0.514	-3.000	<.001	.037	3	1
UCEC	Ku80 →	+0.379	+3.013	.005	.019	2	1
UCEC	MEK1 →	+0.456	+3.000	.031	.037	2	1
UCEC	Annexin-1 →	+1.089	+2.827	<.001	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

SAMD13 survival (RNA) · tumor vs normal (RNA) · all SAMD13 data types