SAMD12

Across TCGA cell cohorts, SAMD12 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SAMD12-associated genes across cancer lineages are GJA8 and CD209. Each is linked with SAMD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAMD12-to-partner and partner-to-SAMD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA8 grouped by SAMD12-low versus SAMD12-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAMD12→partner) and Y-score (partner→SAMD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GJA8 →	+0.016	+3.684	<.001	.006	3	1
SKIN	CD209 →	+0.018	+3.523	<.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GJA8 by SAMD12 expression — SKIN

Explore this box plot interactively →