SAMD12-AS1

Across TCGA pan-cancer cohorts, SAMD12-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated SAMD12-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SAMD12-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SAMD12-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and MESO show a favorable association.

ACC, MESO, and BLCA are the cancer types where SAMD12-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.938	0.442	.002	49	view →
MESO	OS	Quartile	All	0.688	0.402	.010	48	view →
BLCA	DFS	Median	All	0.668	0.564	.005	45	view →
UCEC	DFS	Median	All	0.795	0.876	.002	42	view →
HNSC	OS	Median	IV	0.427	0.261	.007	34	view →
UVM	OS	Tertile	All	0.882	0.502	.015	24	view →
KIRC	OS	Tertile	II,III,IV	0.742	0.630	.016	17	view →
BRCA	DFS	Quartile	III,IV	0.931	0.767	.001	17	view →
THYM	OS	Tertile	II,III,IV	0.633	0.954	.008	12	view →
THCA	DFS	Quartile	IV	0.389	0.925	.006	12	view →
PRAD	DFS	Median	All	0.964	0.902	.002	12	view →
KIRP	OS	Median	All	0.630	0.900	.034	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

SAMD12-AS1–ACC (DFS)

Open the ACC breakdown →