SAMD11P1

Across TCGA pan-cancer cohorts, SAMD11P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SAMD11P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SAMD11P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SAMD11P1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, KICH, and BRCA are the cancer types where SAMD11P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SAMD11P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.027	.010	7	view →
KICH	All	All	−0.049	.009	3	view →
BRCA	All	III,IV	+0.025	.044	2	view →
THCA	All	II,III,IV	−0.061	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SAMD11P1–KIRC

Open the KIRC breakdown →