Across TCGA pan-cancer cohorts, SALL4P2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SALL4P2’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SALL4P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SALL4P2 is over-expressed in tumor.
HNSC, BRCA, and LUSC are the cancer types where SALL4P2 tumor–normal differential expression is most reproducible.