SALL1

Across TCGA cell cohorts, SALL1 mutation is significantly associated with the RNA expression of many other genes, with 590 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SALL1-associated genes across cancer lineages are OR2B2, ACSM4, and DYTN. Each is linked with SALL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SALL1-to-partner and partner-to-SALL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2B2 grouped by SALL1-low versus SALL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SALL1→partner) and Y-score (partner→SALL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2B2 →	+0.015	+1.888	.008	.001	3	3
SOFT_TISSUE	ACSM4 →	+0.039	+5.369	<.001	.004	3	2
OESOPHAGUS	DYTN →	+0.071	+3.273	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR56A5 →	+0.073	+4.887	<.001	.009	3	2
LARGE_INTESTINE	ZBED4 →	+0.459	+1.949	.003	.002	3	2
LARGE_INTESTINE	PGBD1 →	+0.608	+3.169	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 590 associations by consensus.

OR2B2 by SALL1 expression — LARGE_INTESTINE

Explore this box plot interactively →