SAE1

Across TCGA patient cohorts, SAE1 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,854 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SAE1-associated proteins across cancer lineages are ADNP, CHERP, and HNRNPR. Each is linked with SAE1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SAE1-to-partner and partner-to-SAE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAE1 versus ADNP in GBM, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAE1→partner) and Y-score (partner→SAE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADNP →	+0.402	+0.541	<.001	<.001	3	10
LSCC	CHERP →	+0.260	+0.245	<.001	<.001	3	10
GBM	HNRNPR →	+0.315	+0.382	<.001	<.001	3	10
LSCC	TBCB →	+0.390	+0.353	<.001	<.001	3	10
GBM	U2AF2 →	+0.274	+0.477	<.001	<.001	3	10
GBM	UBA2 →	+0.553	+0.610	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,854 associations by consensus.

SAE1 vs ADNP — GBM

Explore this scatter interactively →