Across TCGA patient cohorts, SACM1L protein abundance is significantly associated with the RNA expression of many other genes, with 13,171 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SACM1L-associated genes across cancer lineages are NUP85, WDCP, and ZNF146. Each is linked with SACM1L in more than 5 cancer types. Because this analysis shows association rather than direction, both SACM1L-to-partner and partner-to-SACM1L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SACM1L→partner) and Y-score (partner→SACM1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUP85 →	-0.593	-0.491	<.001	<.001	3	5
LSCC	WDCP →	-0.552	-0.191	<.001	.003	3	5
LSCC	ZNF146 →	-0.529	-0.197	.001	.005	2	6
UCEC	INF2 →	-0.766	-0.502	<.001	<.001	3	5
UCEC	ZNF343 →	-0.651	-0.542	<.001	<.001	3	5
UCEC	ITGB1BP1 →	-0.486	-0.535	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,171 associations by consensus.

Exploration

SACM1L survival (RNA) · tumor vs normal (RNA) · all SACM1L data types