Across TCGA patient cohorts, SACM1L protein abundance is significantly associated with the protein abundance of many other proteins, with 19,461 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SACM1L-associated proteins across cancer lineages are ANO10, ARL6IP5, and MOSPD2. Each is linked with SACM1L in more than 8 cancer types. Because this analysis shows association rather than direction, both SACM1L-to-partner and partner-to-SACM1L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SACM1L→partner) and Y-score (partner→SACM1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANO10 →	+0.996	+0.616	<.001	<.001	3	9
BRCA	ARL6IP5 →	+0.587	+0.533	<.001	<.001	3	8
UCEC	MOSPD2 →	+0.428	+0.528	<.001	<.001	3	8
UCEC	PNPLA6 →	+0.308	+0.508	<.001	<.001	3	8
BRCA	MAGT1 →	+0.753	+0.667	<.001	<.001	3	8
BRCA	RFT1 →	+0.645	+0.660	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,461 associations by consensus.

Exploration

SACM1L survival (RNA) · tumor vs normal (RNA) · all SACM1L data types