SAAL1

Across TCGA pan-cancer cohorts, SAAL1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SAAL1 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SAAL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SAAL1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

PDAC, HNSC, and COAD are the cancer types where SAAL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.347	0.829	.006	13	view →
HNSC	OS	Quartile	All	0.170	1.000	.017	12	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
LUAD	OS	Quartile	II,III,IV	0.224	0.747	.025	5	view →
LSCC	DFS	Quartile	All	0.804	0.562	.023	3	view →
UCEC	DFS	Quartile	All	0.898	1.000	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SAAL1–PDAC (OS)

Open the PDAC breakdown →