SAA4

Across TCGA patient cohorts, SAA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,471 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAA4-associated proteins across cancer lineages are LCN2, ITGAM, and MNDA. Each is linked with SAA4 in more than 6 cancer types. Because this analysis shows association rather than direction, both SAA4-to-partner and partner-to-SAA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAA4 versus LCN2 in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA4→partner) and Y-score (partner→SAA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCN2 →	+1.469	+0.720	<.001	<.001	3	7
GBM	ITGAM →	+0.861	+0.806	<.001	<.001	3	6
GBM	MNDA →	+0.671	+0.451	<.001	<.001	3	6
PDAC	S100A8 →	+1.234	+0.686	<.001	<.001	3	5
GBM	S100A9 →	+1.291	+0.768	<.001	<.001	3	5
GBM	S100A9_T113 →	+1.232	+0.746	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,471 associations by consensus.

SAA4 vs LCN2 — GBM

Explore this scatter interactively →