SAA4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SAA4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SAA4-associated genes across cancer lineages are RNU6-754P. Each is linked with SAA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAA4-to-partner and partner-to-SAA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-754P grouped by SAA4-low versus SAA4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA4→partner) and Y-score (partner→SAA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU6-754P →+0.248+7.816<.001.00831
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RNU6-754P by SAA4 expression — SKCM

Box plot of RNU6-754P in SAA4-low vs SAA4-high samples in SKCM.

Explore this box plot interactively →

Exploration