SAA2

Across TCGA patient cohorts, SAA2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAA2-associated genes across cancer lineages are TREM1, TPGS2, and AP1S3. Each is linked with SAA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAA2-to-partner and partner-to-SAA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAA2 versus TREM1 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAA2→partner) and Y-score (partner→SAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TREM1 →	+1.333	+1.209	.007	.005	3	3
HNSC	TPGS2 →	-0.524	-0.682	<.001	<.001	3	3
COAD	AP1S3 →	+0.658	+0.670	.002	.003	3	2
LSCC	ZNF830 →	-0.350	-0.488	<.001	.008	3	2
LUAD	MEFV →	+0.568	+1.256	.009	.001	3	2
UCEC	HAMP →	+0.845	+1.002	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,777 associations by consensus.

SAA2 vs TREM1 — UCEC

Explore this scatter interactively →